Tyrphostin-like compounds with ubiquitin modulatory activity as possible therapeutic agents for multiple myeloma

Keyphrases

• Multiple Myeloma 100%
• Ubiquitin 100%
• Therapeutic Agents 100%
• Tyrphostin 100%
• Modulatory Activity 100%
• Apoptosis 50%
• Cyclization 50%
• Small Molecules 50%
• Signal Transduction 50%
• Malignancy 50%
• Solution Phase 50%
• Side Chain 50%
• Molecular Orbital 50%
• Solid Phase 50%
• Myeloma Cells 50%
• Apoptosis Induction 50%
• Unsaturated Ketones 50%
• Novel Regulator 50%
• B3LYP 50%
• Bulky Groups 50%
• Deubiquitinase 50%
• Fukui 50%
• MM-1 50%
• Ubiquitin-like Protein 50%
• Compound Activity 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Multiple Myeloma 100%
• Tyrphostin 100%
• Ubiquitin 100%
• Deubiquitinase 50%
• Molecular Orbital 50%
• Ketone 50%

Chemistry

• Ubiquitins 100%
• DFT-B3LYP Calculation 50%
• Molecular Orbital 50%
• Ketone 50%
• Signal Transduction 50%
• Ubiquitylation 50%