Ultrafast Backbone Protonation in Channelrhodopsin-1 Captured by Polarization Resolved Fs Vis-pump—IR-Probe Spectroscopy and Computational Methods

Keyphrases

• Computational Methods 100%
• Polarization-resolved 100%
• Ultrafast 100%
• Spectroscopic Techniques 100%
• Channelrhodopsin-2 (ChR2) 100%
• Protonation 100%
• Counterion 50%
• Proton Transfer 50%
• Protein Changes 50%
• Channel Conductivity 50%
• Protein Backbone 25%
• Protein Dynamics 25%
• Retinal Chromophore 25%
• Isomerization 25%
• Protein Channel 25%
• Mid-infrared 25%
• Photoisomerization 25%
• Geometry Optimization 25%
• Homology Modeling 25%
• Photoproducts 25%
• Optogenetics 25%
• Picosecond 25%
• Quantum Mechanics-molecular Mechanics 25%
• Ultrafast Spectroscopy 25%
• Light Excitation 25%
• Carboxylate Group 25%
• Chlamydomonas 25%
• Proton Dynamics 25%
• Deprotonation 25%
• Initial Reaction 25%
• Light-gated Ion Channel 25%

Biochemistry, Genetics and Molecular Biology

• Protonation 100%
• Channelrhodopsin 100%
• Dynamics 50%
• Proton Transport 50%
• Conductance 50%
• Molecular Mechanic 25%
• Quantum Mechanics 25%
• Homology Modeling 25%
• Isomerization 25%
• Optogenetics 25%
• Chlamydomonas 25%
• Deprotonation 25%
• Light-Gated Ion Channel 25%
• Ultrafast Spectroscopy 25%
• Protein Dynamics 25%
• Retinal 25%

Chemistry

• protonation 100%
• Proton Transfer 50%
• Counterion 50%
• Purity 25%
• Isomerization 25%
• Photoisomerization 25%
• Molecular Mechanic 25%
• Ultrafast Spectroscopy 25%
• Mid-IR Spectroscopy 25%
• Deprotonation 25%
• Chromophore 25%
• Retinal 25%
• Carboxylic Acid 25%