Ultrastructural and biochemical study of extracellular matrix vesicles in normal alveolar bone of rats

I. A. Bab, A. Muhlrad, J. Sela*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

The occurrence of vesicles in the extracellular matrix of alveolar bone of normal young rats was demonstrated by both ultrastructural and enzymatic studies. Transmission electron microscopy revealed abundant vesicles in the matrix. The presence of hydroxyapatite crystals, both within the vesicles and in the matrix, was affiliated with rupture of the vesicular membrane. Calcifying nodules were scarce. High levels of both specific and total activities of alkalineand pyrophosphatases were found in the fraction of isolated vesicles. This fraction also showed activities of different ATPases and acid phosphatase.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalCell and Tissue Research
Volume202
Issue number1
DOIs
StatePublished - Oct 1979

Keywords

  • Matrix vesicles
  • Normal bone
  • Rat

Fingerprint

Dive into the research topics of 'Ultrastructural and biochemical study of extracellular matrix vesicles in normal alveolar bone of rats'. Together they form a unique fingerprint.

Cite this