Unexpected distribution of immobilized microorganisms within alginate beads

C. Zohar-Perez, I. Chet, A. Nussinovitch*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Immobilization refers to the prevention of free cell movement by natural or artificial means. It has always been assumed that immediately after an immobilization procedure is performed, cells are distributed homogeneously in the beads that entrap them. However, in this study, Escherichia coli and Trichoderma asperellum distribution in alginate-gel beads was found to be nonhomogeneous. In fact, there was a greater presence of cells on the surface of the alginate beads than in their cores.

Original languageAmerican English
Pages (from-to)671-674
Number of pages4
JournalBiotechnology and Bioengineering
Issue number5
StatePublished - 5 Dec 2004


  • Agarose
  • Alginate
  • Cell immobilization
  • Escherichia coli
  • Trichoderma asperellum


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