Valproic acid hypersensitivity and desensitization

Ori Toker; Yuval Tal; Liran Horev; Dorit Shmoeli; Tal Gilboa

doi:10.1111/dmcn.12835

Valproic acid hypersensitivity and desensitization

Ori Toker^*, Yuval Tal, Liran Horev, Dorit Shmoeli, Tal Gilboa

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Rash, a hypersensitivity reaction, is a common cause of withdrawal from an effective antiepileptic drug (AED) in patients with epilepsy. We present a case of successful desensitization to valproic acid in a 12-year-old male with childhood absence epilepsy and a hypersensitivity reaction, whose epilepsy did not respond to other AEDs. Desensitization is a practical therapeutic solution for patients who develop a non-life-threatening hypersensitivity reaction to an AED for which there may be no substitute.

Original language	English
Pages (from-to)	1076-1078
Number of pages	3
Journal	Developmental Medicine and Child Neurology
Volume	57
Issue number	11
DOIs	https://doi.org/10.1111/dmcn.12835
State	Published - Nov 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015 Mac Keith Press.

Access to Document

10.1111/dmcn.12835

Cite this

@article{4c1bea33d39441eba71dd4dd7342f0fa,

title = "Valproic acid hypersensitivity and desensitization",

abstract = "Rash, a hypersensitivity reaction, is a common cause of withdrawal from an effective antiepileptic drug (AED) in patients with epilepsy. We present a case of successful desensitization to valproic acid in a 12-year-old male with childhood absence epilepsy and a hypersensitivity reaction, whose epilepsy did not respond to other AEDs. Desensitization is a practical therapeutic solution for patients who develop a non-life-threatening hypersensitivity reaction to an AED for which there may be no substitute.",

author = "Ori Toker and Yuval Tal and Liran Horev and Dorit Shmoeli and Tal Gilboa",

note = "Publisher Copyright: {\textcopyright} 2015 Mac Keith Press.",

year = "2015",

month = nov,

doi = "10.1111/dmcn.12835",

language = "אנגלית",

volume = "57",

pages = "1076--1078",

journal = "Developmental Medicine and Child Neurology",

issn = "0012-1622",

publisher = "Wiley-Blackwell",

number = "11",

}

TY - JOUR

T1 - Valproic acid hypersensitivity and desensitization

AU - Toker, Ori

AU - Tal, Yuval

AU - Horev, Liran

AU - Shmoeli, Dorit

AU - Gilboa, Tal

PY - 2015/11

Y1 - 2015/11

N2 - Rash, a hypersensitivity reaction, is a common cause of withdrawal from an effective antiepileptic drug (AED) in patients with epilepsy. We present a case of successful desensitization to valproic acid in a 12-year-old male with childhood absence epilepsy and a hypersensitivity reaction, whose epilepsy did not respond to other AEDs. Desensitization is a practical therapeutic solution for patients who develop a non-life-threatening hypersensitivity reaction to an AED for which there may be no substitute.

AB - Rash, a hypersensitivity reaction, is a common cause of withdrawal from an effective antiepileptic drug (AED) in patients with epilepsy. We present a case of successful desensitization to valproic acid in a 12-year-old male with childhood absence epilepsy and a hypersensitivity reaction, whose epilepsy did not respond to other AEDs. Desensitization is a practical therapeutic solution for patients who develop a non-life-threatening hypersensitivity reaction to an AED for which there may be no substitute.

UR - http://www.scopus.com/inward/record.url?scp=84943197718&partnerID=8YFLogxK

U2 - 10.1111/dmcn.12835

DO - 10.1111/dmcn.12835

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 26096509

AN - SCOPUS:84943197718

SN - 0012-1622

VL - 57

SP - 1076

EP - 1078

JO - Developmental Medicine and Child Neurology

JF - Developmental Medicine and Child Neurology

IS - 11

ER -

Valproic acid hypersensitivity and desensitization

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this