Variance function estimation in quantitative mass spectrometry with application to iTRAQ labeling

Keyphrases

• Quantitative Mass Spectrometry 100%
• Isobaric Tags for Relative 100%
• Relative Quantitation 100%
• Absolute Quantitation 100%
• Variance Function 100%
• Variance Function Estimation 100%
• Confidence Interval 25%
• Isotopic Labeling 25%
• Mass Spectrometer 25%
• Mass Spectrometry Analysis 25%
• Signaling Cascades 25%
• Biological Samples 25%
• Oncogenic mutations 25%
• Stability over Time 25%
• Aberrant Signaling 25%
• Nuisance Parameter 25%
• Number of Replicates 25%
• Peptide Amount 25%

Biochemistry, Genetics and Molecular Biology

• Mass Spectrometry 100%
• Isobaric Tag for Relative and Absolute Quantitation 100%
• Proteomics 33%
• Sample Size 33%
• Isotopic Labeling 33%

Mathematics

• Variance Function 100%
• Confidence Interval 20%
• Isotopic 20%
• Replicate 20%
• Nuisance Parameter 20%
• Estimated Variance 20%
• Signalling Cascade 20%