Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α₁β₁/α₂β₁ integrins with antiangiogenic activity

Keyphrases

• Cyclic Peptide 100%
• Linear Peptide 100%
• Integrin 100%
• Antiangiogenic Activity 100%
• Dual Antagonist 100%
• Obtustatin 100%
• IC50 50%
• Wound Healing 50%
• Vascular Endothelial Growth Factor 50%
• Vascularization 50%
• Bioactive 50%
• Endothelial Cells 50%
• Protein Family 50%
• Collagen 50%
• Angiogenesis 50%
• Cancer Therapy 50%
• Adhesion 50%
• Conformational Ensemble 50%
• Shared Space 50%
• Human Serum 50%
• Intravenous Injection 50%
• Glioma 50%
• Binding Motif 50%
• Tube Formation Assay 50%
• Anti-angiogenesis 50%
• Matrigel 50%
• In Vivo Efficacy 50%
• High Potency 50%
• Disintegrin 50%
• Acute Toxicity 50%
• Integrin Antagonist 50%
• Migration Inhibition 50%
• Biologic Activity 50%
• Endothelial Cell Culture 50%
• Chick Chorioallantoic Membrane Assay 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Antiangiogenic 100%
• Integrin 100%
• Cyclopeptide 66%
• Arginine 33%
• IC50 33%
• Malignant Neoplasm 33%
• Wound Healing 33%
• Vasculotropin 33%
• Cell Culture 33%
• Matrigel 33%
• Lead Compound 33%
• Acute Toxicity 33%
• Disintegrin 33%