Viral aetiology of haemangiosarcoma outbreaks among layer hens

Haim Burstein, Moshe Kotler

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Outbreaks of neoplastic disease defined as haemangiosarcoma occurred among layer flocks of chickens in Israel. The disease caused bleeding tumours in the skin and internal organs of young layers, followed by anaemia, cessation of egg production and high mortality up to 20%. Avian leukosis virus was isolated from tumour cells which contain several viral DNA copies integrated in the cell genome. The isolated virus induced haemangiosarcomas in more than 30% of birds inoculated on the day of hatching. Congenital transmission of viruses from tumour-bearing hens to their offspring was observed.

Original languageEnglish
Pages (from-to)715-726
Number of pages12
JournalAvian Pathology
Volume13
Issue number4
DOIs
StatePublished - 1 Oct 1984

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