Viral ion channel proteins in model membranes: A comparative study by X-ray reflectivity

Z. Khattari; E. Arbely; I. T. Arkin; T. Salditt

doi:10.1007/s00249-006-0099-x

Viral ion channel proteins in model membranes: A comparative study by X-ray reflectivity

Z. Khattari, E. Arbely, I. T. Arkin, T. Salditt^*

^*Corresponding author for this work

Department of Biological Chemistry

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We have investigated the effect of the transmembrane domain of three viral ion channel proteins on the lipid bilayer structure by X-ray reflectivity and scattering from oriented planar bilayers. The proteins show a similar effect on the lipid bilayer structural parameters: an increase in the lipid bilayer hydrophobic core, a decrease in the amplitude of the vertical density profile and a systematic change in the ordering of the acyl chains as a function of protein-to-lipid ratio. These results are discussed in a comparative view.

Original language	English
Pages (from-to)	45-55
Number of pages	11
Journal	European Biophysics Journal
Volume	36
Issue number	1
DOIs	https://doi.org/10.1007/s00249-006-0099-x
State	Published - Dec 2006

Bibliographical note

Funding Information:
Acknowledgment Financial support by the DFG through the German–Israel–Palestine trilateral project SA 7772/6-1 is gratefully acknowledged.

Keywords

Acyl chain correlation
Lipid bilayer
Viral ion channel proteins
X-ray reflectivity

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10.1007/s00249-006-0099-x

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abstract = "We have investigated the effect of the transmembrane domain of three viral ion channel proteins on the lipid bilayer structure by X-ray reflectivity and scattering from oriented planar bilayers. The proteins show a similar effect on the lipid bilayer structural parameters: an increase in the lipid bilayer hydrophobic core, a decrease in the amplitude of the vertical density profile and a systematic change in the ordering of the acyl chains as a function of protein-to-lipid ratio. These results are discussed in a comparative view.",

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author = "Z. Khattari and E. Arbely and Arkin, {I. T.} and T. Salditt",

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AU - Arkin, I. T.

AU - Salditt, T.

N1 - Funding Information: Acknowledgment Financial support by the DFG through the German–Israel–Palestine trilateral project SA 7772/6-1 is gratefully acknowledged.

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AB - We have investigated the effect of the transmembrane domain of three viral ion channel proteins on the lipid bilayer structure by X-ray reflectivity and scattering from oriented planar bilayers. The proteins show a similar effect on the lipid bilayer structural parameters: an increase in the lipid bilayer hydrophobic core, a decrease in the amplitude of the vertical density profile and a systematic change in the ordering of the acyl chains as a function of protein-to-lipid ratio. These results are discussed in a comparative view.

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Viral ion channel proteins in model membranes: A comparative study by X-ray reflectivity

Abstract

Bibliographical note

Keywords

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