VISUALIZATION OF THE FATE OF INACTIVE INFLUENZA VIRUSES IN DAUDI CELLS BY ELECTRON MICROSCOPY.

Gilda Weil-Hillman; Haim Gamliel; Adam Friedmann; Zichria Zakay-Rones

VISUALIZATION OF THE FATE OF INACTIVE INFLUENZA VIRUSES IN DAUDI CELLS BY ELECTRON MICROSCOPY.

Gilda Weil-Hillman^*
, Haim Gamliel
, Adam Friedmann
, Zichria Zakay-Rones

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The replication of active and inactivated influenza viruses in Daudi lymphoma cells was studied by immunofluorescence and electron microscopy. Transmission electron microscopic studies revealed that both the active and the heat-inactivated X47 virus penetrated into the cells. Only the active X47 (XA) virus replicated completely in Daudi cells and produced new viral particles by budding. The formalin-treated X47 virus did not damage or change the cells, and although the viral particles remained adsorbed to the cells, there was little penetration. The heat inactivated X47 virus was visualized as large aggregates of particles adsorbed to the cell surface by electron microscopy.

Original language	English
Pages (from-to)	1687-1693
Number of pages	7
Journal	Scanning Electron Microscopy
Volume	v
State	Published - 1985

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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title = "VISUALIZATION OF THE FATE OF INACTIVE INFLUENZA VIRUSES IN DAUDI CELLS BY ELECTRON MICROSCOPY.",

abstract = "The replication of active and inactivated influenza viruses in Daudi lymphoma cells was studied by immunofluorescence and electron microscopy. Transmission electron microscopic studies revealed that both the active and the heat-inactivated X47 virus penetrated into the cells. Only the active X47 (XA) virus replicated completely in Daudi cells and produced new viral particles by budding. The formalin-treated X47 virus did not damage or change the cells, and although the viral particles remained adsorbed to the cells, there was little penetration. The heat inactivated X47 virus was visualized as large aggregates of particles adsorbed to the cell surface by electron microscopy.",

author = "Gilda Weil-Hillman and Haim Gamliel and Adam Friedmann and Zichria Zakay-Rones",

year = "1985",

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AU - Weil-Hillman, Gilda

AU - Gamliel, Haim

AU - Friedmann, Adam

AU - Zakay-Rones, Zichria

PY - 1985

Y1 - 1985

N2 - The replication of active and inactivated influenza viruses in Daudi lymphoma cells was studied by immunofluorescence and electron microscopy. Transmission electron microscopic studies revealed that both the active and the heat-inactivated X47 virus penetrated into the cells. Only the active X47 (XA) virus replicated completely in Daudi cells and produced new viral particles by budding. The formalin-treated X47 virus did not damage or change the cells, and although the viral particles remained adsorbed to the cells, there was little penetration. The heat inactivated X47 virus was visualized as large aggregates of particles adsorbed to the cell surface by electron microscopy.

AB - The replication of active and inactivated influenza viruses in Daudi lymphoma cells was studied by immunofluorescence and electron microscopy. Transmission electron microscopic studies revealed that both the active and the heat-inactivated X47 virus penetrated into the cells. Only the active X47 (XA) virus replicated completely in Daudi cells and produced new viral particles by budding. The formalin-treated X47 virus did not damage or change the cells, and although the viral particles remained adsorbed to the cells, there was little penetration. The heat inactivated X47 virus was visualized as large aggregates of particles adsorbed to the cell surface by electron microscopy.

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AN - SCOPUS:0022270451

SN - 0586-5581

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JO - Scanning Electron Microscopy

JF - Scanning Electron Microscopy

ER -

VISUALIZATION OF THE FATE OF INACTIVE INFLUENZA VIRUSES IN DAUDI CELLS BY ELECTRON MICROSCOPY.

Abstract

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