Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope

K. M. Shakesheff; M. C. Davies; A. Domb; C. J. Roberts; A. J. Shard; S. J. B. Tendler; P. M. Williams

doi:10.1007/978-1-4757-9325-3_11

Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope

K. M. Shakesheff
, M. C. Davies
, A. Domb
, C. J. Roberts
, A. J. Shard
, S. J. B. Tendler
, P. M. Williams

School of Pharmacy

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The ability of the atomic force microscope (AFM) to observe dynamic polymer/liquid interfaces has been utilized to visualize in situ morphological changes occurring during the biodegradation of polymer surfaces. Using this technique we demonstrate the differential rate of degradation of amorphous and crystalline material and study the kinetics of erosion of an immiscible polymer blend. The use of atomic force microscopy in this applied area of research is furthering our knowledge of the importance of the relationship between surface morphology and degradation kinetics and promises to become an invaluable tool in the evaluation of novel biodegradable materials.

Original language	American English
Title of host publication	Atomic Force Microscopy/Scanning Tunneling Microscopy 2
Editors	Samuel H. Cohen, Marcia L. Lightbody
Place of Publication	Boston, MA
Publisher	Springer US; Imprint: Springer
Pages	93-98
Number of pages	6
ISBN (Print)	978-1-4757-9325-3
DOIs	https://doi.org/10.1007/978-1-4757-9325-3_11
State	Published - 1997

Access to Document

10.1007/978-1-4757-9325-3_11

Cite this

Shakesheff, K. M., Davies, M. C., Domb, A., Roberts, C. J., Shard, A. J., Tendler, S. J. B., & Williams, P. M. (1997). Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope. In S. H. Cohen, & M. L. Lightbody (Eds.), Atomic Force Microscopy/Scanning Tunneling Microscopy 2 (pp. 93-98). Springer US; Imprint: Springer. https://doi.org/10.1007/978-1-4757-9325-3_11

@inbook{56dd3b7b8bcd46f794c78a3267257c83,

title = "Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope",

abstract = "The ability of the atomic force microscope (AFM) to observe dynamic polymer/liquid interfaces has been utilized to visualize in situ morphological changes occurring during the biodegradation of polymer surfaces. Using this technique we demonstrate the differential rate of degradation of amorphous and crystalline material and study the kinetics of erosion of an immiscible polymer blend. The use of atomic force microscopy in this applied area of research is furthering our knowledge of the importance of the relationship between surface morphology and degradation kinetics and promises to become an invaluable tool in the evaluation of novel biodegradable materials.",

author = "Shakesheff, \{K. M.\} and Davies, \{M. C.\} and A. Domb and Roberts, \{C. J.\} and Shard, \{A. J.\} and Tendler, \{S. J. B.\} and Williams, \{P. M.\}",

year = "1997",

doi = "10.1007/978-1-4757-9325-3\_11",

language = "American English",

isbn = "978-1-4757-9325-3",

pages = "93--98",

editor = "Cohen, \{Samuel H.\} and Lightbody, \{Marcia L.\}",

booktitle = "Atomic Force Microscopy/Scanning Tunneling Microscopy 2",

publisher = "Springer US; Imprint: Springer",

}

Shakesheff, KM, Davies, MC, Domb, A, Roberts, CJ, Shard, AJ, Tendler, SJB & Williams, PM 1997, Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope. in SH Cohen & ML Lightbody (eds), Atomic Force Microscopy/Scanning Tunneling Microscopy 2. Springer US; Imprint: Springer, Boston, MA, pp. 93-98. https://doi.org/10.1007/978-1-4757-9325-3_11

Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope. / Shakesheff, K. M.; Davies, M. C.; Domb, A. et al.
Atomic Force Microscopy/Scanning Tunneling Microscopy 2. ed. / Samuel H. Cohen; Marcia L. Lightbody. Boston, MA: Springer US; Imprint: Springer, 1997. p. 93-98.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope

AU - Shakesheff, K. M.

AU - Davies, M. C.

AU - Domb, A.

AU - Roberts, C. J.

AU - Shard, A. J.

AU - Tendler, S. J. B.

AU - Williams, P. M.

PY - 1997

Y1 - 1997

N2 - The ability of the atomic force microscope (AFM) to observe dynamic polymer/liquid interfaces has been utilized to visualize in situ morphological changes occurring during the biodegradation of polymer surfaces. Using this technique we demonstrate the differential rate of degradation of amorphous and crystalline material and study the kinetics of erosion of an immiscible polymer blend. The use of atomic force microscopy in this applied area of research is furthering our knowledge of the importance of the relationship between surface morphology and degradation kinetics and promises to become an invaluable tool in the evaluation of novel biodegradable materials.

AB - The ability of the atomic force microscope (AFM) to observe dynamic polymer/liquid interfaces has been utilized to visualize in situ morphological changes occurring during the biodegradation of polymer surfaces. Using this technique we demonstrate the differential rate of degradation of amorphous and crystalline material and study the kinetics of erosion of an immiscible polymer blend. The use of atomic force microscopy in this applied area of research is furthering our knowledge of the importance of the relationship between surface morphology and degradation kinetics and promises to become an invaluable tool in the evaluation of novel biodegradable materials.

U2 - 10.1007/978-1-4757-9325-3_11

DO - 10.1007/978-1-4757-9325-3_11

M3 - Chapter

SN - 978-1-4757-9325-3

SP - 93

EP - 98

BT - Atomic Force Microscopy/Scanning Tunneling Microscopy 2

A2 - Cohen, Samuel H.

A2 - Lightbody, Marcia L.

PB - Springer US; Imprint: Springer

CY - Boston, MA

ER -

Visualization of the Surface Degradation of Biomedical Polymers in Situ with an Atomic Force Microscope

Abstract

Access to Document

Fingerprint

Cite this