What determines whether chromosomes segregate reductionally or equationally in meiosis?

Giora Simchen*, Yasser Hugerat

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations

Abstract

Normal meiosis consists of a single round of DNA replication followed by two nuclear divisions. In the 1st division the chromosomes segregate reductionally whereas in the 2nd division they segregate equationally (as they do in mitosis). In certain yeast mutants, a single‐division meiosis takes place, in which some chromosomes segregate reductionally while others divide equationally. This autonomous segregation behaviour of individual chromosomes on a common spindle is determined by the centromeres they carry. The relationship between reductional segregation of a pair of chromosomes and their earlier recombinational history is also discussed.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBioEssays
Volume15
Issue number1
DOIs
StatePublished - Jan 1993

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