What Is the Relationship between Pain and Emotion? Bridging Constructs and Communities

Gadi Gilam*, James J. Gross, Tor D. Wager, Francis J. Keefe, Sean C. Mackey

*Corresponding author for this work

Research output: Contribution to journalComment/debate

50 Scopus citations


Although pain is defined as a sensory and emotional experience, it is traditionally researched and clinically treated separately from emotion. Conceptual and mechanistic relationships between these constructs highlight the need for better understanding of their bi-directional influences and the value of bridging the pain and emotion research and clinical communities.

Original languageAmerican English
Pages (from-to)17-21
Number of pages5
Issue number1
StatePublished - 8 Jul 2020
Externally publishedYes

Bibliographical note

Funding Information:
S.C.M. and G.G. thank the Redlich Pain Research Endowment and the Feldman Family Foundation Pain Research Fund for their financial support. The following National Institutes of Health grants provided further financial support: R01 NS109450 , K24 DA029262 , R01 DA035484 , and P01 AT006651 (to S.C.M.); R01 MH076136 , R01 DA046064 , and R01 MH116026 (to T.D.W.); and P30 AG064201 , R01 AG058702 , UG1 CA189824 , and U2C NR014637 (to F.J.K.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Publisher Copyright:
© 2020 Elsevier Inc.


  • affect
  • brain
  • chronic pain
  • emotion
  • interoception
  • mental health
  • nociception
  • noxious
  • pain
  • subjective experience


Dive into the research topics of 'What Is the Relationship between Pain and Emotion? Bridging Constructs and Communities'. Together they form a unique fingerprint.

Cite this